Chemical integration

The chemical basis of host nest detection and chemical integration in a cuckoo paper wasp.

Insect social life is governed by chemicals. A great number of studies have demonstrated that the blend of hydrocarbons present on the cuticle (CHCs) plays a pivotal role in intra- and inter-specific communication. It is not surprising, therefore, that social parasites, specialized in exploiting the costly parental care provided by host workers, exploit the host chemical communication system to...

Integration of chemical information with protein sequences and 3D structures

The Protein Data Bank (PDB) contains a wealth of small molecule macro molecule complexes the study of which contribute enormously to our understanding of the interactions. However, exploiting and mining this treasure trove of data requires advanced analysis and retrieval methods that take into account both types of molecules. One such method is PDBeMotif, that has been developed by the Protein ...

Simultaneous optimization and heat integration of chemical processes

A procedure is proposed for simultaneously handling the problem of optimal heat integration while performing the optimization of process flowsheets. The method is based on including a set of constraints into the nonlinear process optimization problem so as to ensure that the minimum utility target for heat recovery networks is featured. These heat integration constraints, which do not require t...

Physico-chemical Prokaryote Models: Stand-alone Modules and Karyote Integration

STITCH 4: integration of protein–chemical interactions with user data

STITCH is a database of protein-chemical interactions that integrates many sources of experimental and manually curated evidence with text-mining information and interaction predictions. Available at http://stitch.embl.de, the resulting interaction network includes 390 000 chemicals and 3.6 million proteins from 1133 organisms. Compared with the previous version, the number of high-confidence p...